Fig. 2: Cryo-EM reconstruction of the amyloid fibril.
From: Cryo-EM structure of an ATTRwt amyloid fibril from systemic non-hereditary transthyretin amyloidosis

a Scanning electron microscopy image of ATTRwt fibrils after platinum side shadowing. The red markers and boxes indicate vaguely visible crossovers. Scale bar = 200 nm. b Cross-section of one layer of a partly transparent reconstructed 3D map superimposed with the spearhead shaped molecular model. The asterisk marks the internal cavity. c Side view of the reconstructed 3D map. The color coding is consistent with panel b.