Table 2 Constituents of the Podocin interactome determined by meAP-MS, together with annotation of subcellular localization and primary function(s) indicated in literature and public databases
From: A slit-diaphragm-associated protein network for dynamic control of renal filtration
ID | Acc. No. | Name | Topology/localization | Function |
|---|---|---|---|---|
PODO | Q91X05 | Podocin | 1 IM | Scaffold |
NPHN | Q9QZS7 | Nephrin | 1 TM | Cell adhesion, signaling |
KIRR1 | Q80W68 | Neph1 | 1 TM | Cell adhesion, signaling |
ANPRA* | P18293 | ANPRA | 1 TM | Receptor mediated signaling, guanylyl cyclase |
MERTK* | Q60805 | MerTK | 1 TM | Receptor kinase |
PTPRO* | E9Q612 | R-PTP-O | 1 TM | Receptor phosphatase, cell adhesion |
IQGA2* | Q3UQ44 | IQGAP2 | cytoplasmic/membrane associated | Signaling |
DEND | Q80TS7 | Dendrin | membrane associated/nuclear | Signaling, apoptosis |
CD81* | P35762 | CD81 antigen | 4 TMs | Scaffold/signaling |
MAGI2 | Q9WVQ1 | MAGI-2 | membrane associated | Scaffold |
AMPE* | P16406 | Glutamyl aminopeptidase | 1 TM | Glutamyl aminopeptidase |
ITA3* | Q62470 | Integrin alpha-3 | 1 TM | Cell adhesion |
CTL2* | Q8BY89 | Choline transporter-like protein 2 | 10 TMs | Transporter |
MFSD1* | Q9DC37 | MFSD1 | 11 or 12 TMs | Transporter |
S13A3* | Q91Y63 | Solute carrier family 13 member 3 | 11 TMs/1 IM | Transporter |
S22AJ* | Q8VCA0 | Solute carrier family 22 member 19 | 11 TMs | Transporter |
S6A19* | Q9D687 | Solute carrier family 6 member 19 | 12 TMs | Transporter |
SC5AB* | Q8K0E3 | Solute carrier family 5 member 11 | 14 TMs | Transporter |
SLC31* | Q91WV7 | Solute carrier family 3 member 1 | 1 TM | Transporter |
ABC-A9* | Q8K449 | ABC sub-family A member 9 | 14 TMs | Transporter |
