Fig. 3: Atomic structures of CDTa-bound CDTb-pores. | Nature Communications

Fig. 3: Atomic structures of CDTa-bound CDTb-pores.

From: Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile

Fig. 3

a Domain structure of CDTa. b Domain structure of CDTb after cleavage of the N-terminal pro-sequence. c Structure of long CDTa-bound CDTb-pore. d Structure of short CDTa-bound CDTb-pore. Colors are the same as those in panels a, b. e Cut-away view of CDTa-bound CDTb-pore. CDTb-pore is shown as a surface model, in which Ca-edges are colored by respective protomers. CDTa is shown as a ribbon. f CDTb-pore diameters measured from the CDTa-bound state (short) using HOLE software53. g Interaction between CDTa and CDTb. CDTa structure is shown as a ribbon. Constrictions (Ca-edges and NSS-loops) of the CDTb-pore are shown as surface models colored by respective protomers.

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