Table 1 Estimated parameter values

From: p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition

\(r\)

\(\varGamma\)

\(\lambda\)

\(\delta\)

Reference

0.1

3.5/week

1.9/week

0.29

15

0.06

3.7/week

2.9/week

0.32

16

0.1

5.4/week

2.9/week

0.19

16

  1. We further tested the robustness of the parameter estimates by perturbing estimates of λ and r, find that there was a broad agreement between simulations and observations (Supplementary Fig. 2b, c).
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