Fig. 5: Oncogenic subpopulation has implications for EEC patients' survival.
a According to the TCGA EEC data, the expression of LCN2, SAA1, and SAA2 was significantly elevated in EEC subjects (t test, two-sided, p values are noted). Normal samples: n = 35, EEC samples: n = 411. The expression level of each gene is visualized by log2(TPM + 1). Bar plots show the median (center), 25–75 percentile (box), and lower whisker = smallest observation greater than or equal to lower hinge−1.5 * IQR (interquartile range); upper whisker = largest observation less than or equal to upper hinge + 1.5 * IQR (Source data are provided as a Source Data file). b Combination with LCN2 and SAA1/2 predicted a disease outcome across TCGA EEC cohorts. The median was set as the cut-off value to stratify EEC patients into low-risk and high-risk groups. The endpoint was 100 months. Survival curves were compared via Log–rank test and visualized by Kaplan–Meier method.
