Fig. 1: Structure of LlPC.
From: CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase
a Atomic structure of LlPC (pdb code 5vyz30) subunit colored by different domains, together with the distribution of these domains in the primary structure of the protein. The lysine at the BCCP domain is the residue where prosthetic biotin is attached. b CryoEM map for LlPC in the presence of acetyl-CoA, substrates and co-factors. The 3D map is colored by estimates of local resolution, being the overall resolution 2.12 Å. c Rendering of the cryoEM map for LlPC depicted in b showing the BC-BC and CT-CT dimers from different layers. Abbreviations stand for: BC biotin carboxylase domain; CT carboxyl transferase domain; BCCP biotin-carboxyl carrier protein domain; PT PC tetramerization domain. This notation is used along all the figures.
