Fig. 2: Structural comparisons and dynamics of the peptide-bound PTH1R-Gs complexes. | Nature Communications

Fig. 2: Structural comparisons and dynamics of the peptide-bound PTH1R-Gs complexes.

From: Molecular insights into the distinct signaling duration for the peptide-induced PTH1R activation

Fig. 2: Structural comparisons and dynamics of the peptide-bound PTH1R-Gs complexes.

a Structural comparisons of the ABL–, PTH– and LA-PTH–bound (PDB 6NBF) PTH1R complexes. Structures were aligned by the TMD of PTH1R. b 3D-variability analysis of the ABL–, PTH– and LA-PTH–bound PTH1R–Gs complexes. Superimposition of models built into density maps corresponding to frame 000 and frame 019 of components 1 in Supplementary Movies. 1, 2 and 3.

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