Fig. 4: Omicron infection in combination with vaccine priming broadens antibody response.
From: Priming conditions shape breadth of neutralizing antibody responses to sarbecoviruses
The % antibody inhibition of ACE2 binding to RBD was determined for a BNT162b2 (n=10 subjects), Coronavac (n = 7 subjects), unvaccinated (n = 5 subjects) paired acute (day 0–5) and recovered (1–2 months after illness) patients for Omicron BA.2 infection. a Data represented mean+/− stdev and individual samples. a, b Significant differences in paired pre versus post vaccine responses within vaccine type by one-way Friedmans tests with Dunns multiple comparisons. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Statistics shown for acute versus recovered (b), and ns between Coronavac and BNT162b2 Omicron recovered samples by Ordinary one-way Anova w Sidak’s multiple comparison test.
