Fig. 5: Haplotype resolved expression and replication of protein coding genes.
From: Epigenetic control of chromosome-associated lncRNA genes essential for replication and stability
a 63 protein coding genes display random epigenetic AEI in EB3_2 clones (X-axis: protein coding gene; Y-axis: AEI). b–j Examples of genomic regions that contain protein coding genes that display epigenetic AEI and VERT in the six EB3_2 clones. The left axis shows the replication timing (Early/Late) profiles, and the standard deviation (SD) across each locus is shown below each panel. Outliers in the standard deviation (SD) are highlighted in gray. The right Y-axis shows the AEI, with the stippled rectangles representing protein coding genes and smooth rectangles representing TL. The opaque rectangles show AEI (FDR-BH alpha < =0.01), while the transparent rectangles show bi-allelic expression of protein coding and non-coding transcripts. Chromosome number and genomic positions (megabases) are shown on the X axis. k Functional enrichment analysis of coding genes that display random epigenetic AEI in EB3_2 clones.
