Fig. 8: Global or adipocyte-specific loss of Redd1 prevents HFD-induced hepatic steatosis. | Nature Communications

Fig. 8: Global or adipocyte-specific loss of Redd1 prevents HFD-induced hepatic steatosis.

From: REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-κB activation

Fig. 8: Global or adipocyte-specific loss of Redd1 prevents HFD-induced hepatic steatosis.

a Representative images of H&E-stained liver tissues from HFD-fed Redd1−/−, Redd1ΔAdipoq, Redd1ΔLysM, Redd1KKAA, and control mice, and quantification of hepatic steatosis from H&E-stained liver tissues (n = 6 per group). Scale bars, 100 μm. b Expression levels of Acc, Fasn, and Scd-1 in the liver of HFD-fed Redd1−/−, Redd1ΔAdipoq, Redd1ΔLysM, Redd1KKAA, and their control mice (n = 6 per group). Bar graphs represent mean ± s.e.m. Statistical significance was calculated using an unpaired two-tailed t-test. Source data are provided as a Source Data file.

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