Fig. 3: Synapse composition is altered during the synaptome phenotype waves.

Exemplar puncta spatial distributions of synapse subtypes in single tile images (area 21 × 21 µm) of P7 control (left) and Pax6+/− (right) mouse brain. Whereas the overall puncta density is unchanged, individual synapse subtypes, and therefore the overall subtype composition, are significantly affected by the Pax6+/− mutation.