Table 1 Comparison of method median phase error in hours

From: Tempo: an unsupervised Bayesian algorithm for circadian phase inference in single-cell transcriptomics

Method

Gene set

Aorta SMCs

Aorta fibroblasts

Aorta endothelial cells

Aorta macrophages

Liver hepatocytes

Tempo

All

1.88 (0.03)

2.53 (0.36)

3.39 (0.4)

2.99 (0.01)

3.78 (0.39)

Cyclops

All

5.73 (0.29)

5.84 (0.08)

5.65 (0.54)

5.35 (0.24)

4.66 (0.3)

Cyclops

Core clock

4.62 (1.22)

4.17 (0.74)

5.72 (0.03)

4.08 (0.14)

4.26 (0.27)

Cyclum

All

5.47 (0.44)

5.79 (0.13)

5.74 (0.23)

5.69 (0.31)

5.15 (0.53)

Cyclum

Core clock

5.52 (0.35)

4.79 (0.69)

5.0 (0.45)

4.18 (0.31)

5.65 (0.42)

PCA

All

5.69 (0.0)

6.0 (0.0)

5.84 (0.0)

5.64 (0.0)

5.75 (0.0)

PCA

Core clock

3.39 (0.0)

3.99 (0.0)

5.58 (0.0)

4.41 (0.0)

5.91 (0.0)

  1. Entries denote the mean of median phase errors across five independent runs for each method (in hours). Parenthetical values denote the standard deviation of median phase errors across the five runs (in hours). Of note, PCA is deterministic and its predictions do not differ between runs.