Fig. 4: Genomic and transcriptomic features of the proteomic subclasses. | Nature Communications

Fig. 4: Genomic and transcriptomic features of the proteomic subclasses.

From: Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets

Fig. 4

A Somatic driver alterations in the proteomic subclasses. Genes that were mutated in more than 10 tumors are shown. Bar chart on the right side shows strength of associations between alterations and subclasses, as measured by −log(FDR). FDR was computed by adjusting p-values of Fisher’s exact test with the Benjamini–Hochberg method. Dotted line indicates FDR = 0.05. B Comparison between transcriptomic and proteomic subclasses. Only 204 HCCs where both RNA-Seq and RPPA data was available are shown.

Back to article page