Fig. 6: Prognostic impact of protein expression levels in tumor. | Nature Communications

Fig. 6: Prognostic impact of protein expression levels in tumor.

From: Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets

Fig. 6: Prognostic impact of protein expression levels in tumor.The alternative text for this image may have been generated using AI.

A Hazard ratio for overall survival. For each of 293 proteins measured by RPPA, 259 patients were stratified into high- or low-expression groups based on the median expression levels, and their association with survival was computed using the Cox proportional hazard model. The p-values were adjusted for multiple hypothesis testing using the Benjamini–Hochberg method. Only proteins with FDR < 0.05 are shown. Error bars show 95% confidence intervals. B Kaplan–Meier curves for overall survival and protein expression levels of CDK1, YWHAZ, CDKN2A, and DUSP4 in tumor. For each of the proteins, the number of patients were 129 in high-expression group and 130 in low-expression group. The p-values were computed by the log-rank test without adjustments for multiple comparisons. Source data are provided as a Source Data file.

Back to article page