Fig. 2: Serum EMC10 levels in white weight-loss cohorts. | Nature Communications

Fig. 2: Serum EMC10 levels in white weight-loss cohorts.

From: Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice

Fig. 2: Serum EMC10 levels in white weight-loss cohorts.

A–C BMI, serum EMC10 concentration, or HOMA-IR of white human study participants before and 12 months after bariatric surgery, respectively (n = 50), ***p < 0.001. D–F BMI, serum EMC10 concentration, or HOMA-IR of white human study participants before and 12 months after diet/exercise weight-loss intervention, respectively (n = 50). Comparisons between before and after were performed using Student’s paired t test. G–L Correlations between changes of serum EMC10 levels and changes of BMI, HOMA-IR, HbA1c, serum AST, ALT and TG, respectively, after weight-loss intervention by either bariatric surgery or diet/exercise in the white cohort (n = 100), performed using Pearson’s bivariate correlation. Source data are provided in the Source Data file.

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