Fig. 7: Downregulation of circBNC2 and ctBNC2 associates with epithelial cell G2/M arrest in human fibrotic kidney and liver. | Nature Communications

Fig. 7: Downregulation of circBNC2 and ctBNC2 associates with epithelial cell G2/M arrest in human fibrotic kidney and liver.

From: Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair

Fig. 7: Downregulation of circBNC2 and ctBNC2 associates with epithelial cell G2/M arrest in human fibrotic kidney and liver.The alt text for this image may have been generated using AI.

a–d Representative images showing Masson staining, circBNC2 and ctBNC2 expression, and expression of p-H3 in serial sections of normal kidney and IRI-induced kidney fibrosis (a) and the semi-quantitative data (b–d). For b–d, n = 10 for control, n = 12 for patients with IRI-induced kidney fibrosis). e–j Representative photos showing Masson staining, circBNC2 and ctBNC2 expression, expression of p-H3, TUNEL positive cells, and levels of αSMA, in serial sections of normal liver and hepatitis B virus (HBV)-induced liver fibrosis (e) and the semi-quantitative data (f–j). For f–j, n = 10 tissue in each group. Data are expressed as means ± SD. Two-sided Mann–Whitney U test was used for the comparison of two groups (b, c, d, f, g, h, i, j). Source data are provided as a Source Data file.

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