Fig. 6: Proteomic subtypes of tRCC and associations with genetic features and clinical outcomes.
From: Proteogenomic characterization of MiT family translocation renal cell carcinoma
a Relative abundances of upregulated proteins in the three proteomic subtypes and associations of proteomic subtypes with clinical and genetic features (Fisher’s exact test or Kruskal–Wallis test). b Kaplan–Meier curves of OS and PFS for the three subtypes (two-sided log-rank test). c Upregulated pathways enriched in the three proteomic subtypes. d Ternary plot showing the distribution of significant arm-level events in the three proteomic subtypes. CNA events with significant differences among three proteomic subtypes are indicated (Fisher’s exact test). e GSEA plots showing the trans-effect of 9q deletion. f Cis-effects of 9q deletion in tRCC. P values are derived from two-sided Spearman’s correlation test. g Kaplan–Meier curves of OS for patients with different ATP6V1G1 abundances (two-sided log-rank test).
