Fig. 3: Landscape of human dietary amino acid intake.
From: Amino acid variability, tradeoffs and optimality in human diet
a Workflow for reconstruction of the database consisting of amino acid intake profiles in human dietary data. Food images used with permission from Microsoft. b Comparison between nutrient intake values in the self-reported dietary data and laboratory measurements of nutrient-related metabolites in blood. A two-sided Spearman’s rank correlation test was performed to compute the p-value. c Comparison between total dietary amino acid intake in the reconstructed amino acid intake database and dietary protein intake in the original dietary data. A two-sided Pearson’s correlation test was used to compute the p-value. d Comparison of the reconstructed human dietary amino acid intake values to blood concentrations of amino acids. The dots represent for mean values and error bars for standard deviations. A two-sided Spearman’s rank correlation test was performed to compute the p-value. n = 30899 for dietary intake of amino acids, n = 494 for blood concentration of amino acids. e Comparison of the reconstructed human dietary amino acid intake values to uptake fluxes of amino acids. The dots represent for mean values and error bars for standard deviations. A two-sided Spearman’s rank correlation test was performed to compute the p-value. n = 30899 for dietary intake of amino acids, n = 60 for amino acid uptake fluxes. f Distributions of amino acid intake in human dietary intake profiles. The circles indicate median values. g Principal components analysis (PCA) of amino acid intake values in human dietary intake profiles showing their association with age, sex, ethnicity, and batch of the data.
