Fig. 6: In vivo IOP control with a theranostic smart contact lens. | Nature Communications

Fig. 6: In vivo IOP control with a theranostic smart contact lens.

From: Wireless theranostic smart contact lens for monitoring and control of intraocular pressure in glaucoma

Fig. 6

a Photo-image of a fully integrated theranostic smart contact on rabbit’s eye (scale bar, 5.5 mm). b The correlation of IOP measured with a smart contact lens and a tonometer (R2 = 0.94). c IOP monitoring of right and left eyes with a smart contact lens and a tonometer (n = 3 independent experiments for tonometer). d The IOP change by timolol released from the smart contact lens (n = 25 independent experiments, **P < 0.01). For statistically analysis, one-sided statistical analyses were performed by using one-way analysis of variance. e The IOP control of the theranostic smart contact lens by simultaneous IOP monitoring and timolol release (n = 5 independent experiments for tonometer except for Day 1 (n = 3)). For c–e data are presented as a mean value ± SD.

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