Fig. 2: Cryo-EM structure of the ectodomain of TLR3 in complex with poly(I:C) RNA. | Nature Communications

Fig. 2: Cryo-EM structure of the ectodomain of TLR3 in complex with poly(I:C) RNA.

From: TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand

Fig. 2

a Representative micrographic image of the ectoTLR3-poly(I:C) complex. The picked particles in the cluster (middle) and the dimeric states (right) are marked with green circles. Representative 2D class averages are shown above. b Electron density map of the ectoTLR3-poly(I:C) complex. c The atomic model of the ectoTLR3-poly(I:C) complex. Representative micrograph is from an n = 1087 cryo-EM experiment set.

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