Fig. 5: Variants associated with age of onset plotted onto a wild-type SOD1 dimer representation.
From: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration

Variants associated with a younger age of onset compared to the non-SOD1 ALS population using Cox proportional hazards regression plotted onto PDB structure 2c9v. Codon numbers refer to genomic location.