Fig. 1: Genomic landscape of OS. | Nature Communications

Fig. 1: Genomic landscape of OS.

From: Multi-omics analysis identifies osteosarcoma subtypes with distinct prognosis indicating stratified treatment

Fig. 1

Genetic profile of SGH cohort patients. Each column corresponds to one sample (128 samples are displayed with 9 replicates). A Clinical information of age, sex, position, metastasis, recurrence, pathological classification, ALP (high: >120 U/ml) and clinical Enneking stages. Genetic information included TMB, HRD score (high: >42), ploidy and tumor purity. B Somatic mutated genes that were associated with genome maintenance, oncogene/tumor suppressor gene (Oncogene/TSG), cell cycle, epigenetic and transcriptional regulation; C Cancer-related genes located in significant CNA peaks identified by GISTIC 2.0 with q value <0.25. The number and percentage of mutations and CNAs for each of the genes are shown on the right.

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