Fig. 2: Characterisation of MIL-101 nanoparticles and their degradation in PBS. | Nature Communications

Fig. 2: Characterisation of MIL-101 nanoparticles and their degradation in PBS.

From: Flash drug release from nanoparticles accumulated in the targeted blood vessels facilitates the tumour treatment

Fig. 2

a Schematic representation of the pore structure of MIL-101 nanoparticles (NPs). b Scanning electron microscopy (SEM) micrograph of MIL-101 NPs, n = 1 sample. Scale bar = 1 µm. c Hydrodynamic size distribution of MIL-101 NPs in water, n = 1 sample, 3 repetitions. d Extinction spectra of MIL-101 NPs 24-h post incubation in ethanol (green), water (blue), and PBS buffer (red). Inset—images of cuvettes with NP solutions in dispersants, n = 1 measurement. e SEM images of two droplets of MIL-101 NPs of the same volume and concentration 24-h post incubation in water (left) and PBS (right), n = 1 experiment. Scale bars = 500 μm. f Mass analysis of MIL-101 NP samples before (blue) and after degradation (red), n = 3 samples. g Photoacoustic analysis of MIL-101 NP degradation kinetics in water (blue) or PBS (red) at concentrations 200 mg L−1 (top) and 40 mg L−1 (bottom), n = 3 samples. In f, g data are presented as mean values ± SD.

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