Table 1 Free energy differences calculated from SAFEP
Local Environment | POPE to POPC (kcal/mol) | POPE to POPG (kcal/mol) | |
|---|---|---|---|
Transformation of Bulk Lipid | 2POPC:1POPE: 1POPG | 1 ± 1 | −17 ± 2 |
3POPC:1POPG | −1 ± 1 | −21 ± 3 | |
POPC | −1 ± 1 | −17 ± 1 | |
Transformation of Bound Lipid | WT CA | 5 ± 1 | −19 ± 2 |
ELIC5 CA | 3 ± 1 | −24 ± 2 |
