Table 2 Description of differences between the newly sequenced and de novo assembled H37Rv strains, TMC102, NR123 and H37Rv1988 identified by DNAdiff

From: A comprehensive update to the Mycobacterium tuberculosis H37Rv reference genome

R#

Description

R11

117 bp insertion in PE_PGRS5 (rv0297) in TMC102 and H37Rv1998

R12

123 bp insertion in intergenic region between rv0487 and rv0488 in TMC102 and H37Rv1998

R13

Additional 1356 bp IS6110 transposon element insertion between plcD (rv1755c) and cut1(rv1758) in TMC102

R14

114 bp insertion in rv2090 (Probable 5’−3’ exonuclease) in TMC102

R15

14 bp tandem duplication between Nrdh (Rv3053c) and Rv3054c in TMC102

R16

1356 bp IS6110 transposon element insertion between higA (Rv1956) and another IS6110 transposon in TMC102

R17

9 bp tandem duplication in PE_PGRS51 (rv3367) in TMC102

R18

51 bp insertion in rv2680 in NR123 and H37Rv1998

R19

59 bp insertion in intergenic region between rv2980 and ddlA (rv2981c) in H37Rv1998

R20

9 bp tandem duplication in PE_PGRS57 (rv3514) in H37Rv1998