Fig. 4: SOTIP stratifies known layers in brain tissues.
From: SOTIP is a versatile method for microenvironment modeling with spatial omics data
a–d Human dorsolateral prefrontal cortex dataset with 10x Visium. a Spatial arrangement illustration for typical 10x Visium dataset. b Ground truth annotation for slice 151673. c Spatial domain detected by SOTIP. The labels are not consecutive because SOTIP follows a hierarchical merging scheme. d Boxplots summarize the detection accuracy (y-axis) of four methods (x-axis) in all 12 samples. The definition of each box can be found in Methods. e–h mouse somatosensory cortex dataset with osmFISH. e Spatial arrangement illustration for typical osmFISH dataset. f Ground truth of regional annotation for the osmFISH sample. g, h Spatial domains identified by SpaGCN (g) and SOTIP (h). Source data are provided as a Source Data file.
