Fig. 5: Comparison of MsbA LPS binding sites.
From: Structural basis for lipid and copper regulation of the ABC transporter MsbA
Structures are shown in cartoon representation with lipid (if present) shown in orange spheres. Two views are shown (0 and 90°). Shown is the a exterior binding site (this work), b interior binding site (PDB 6BPL)6,17, and c putative exterior binding site (PDB 6BL6)19,64. In panel c, the density was not clear enough to model the lipid and putative site is denoted by a red circle19. d Sequence logo of KDL interacting residues (83, 87, 188, 236, 238, 240, and 243) based on an alignment of 258 MsbA sequences from across the bacterial phylogeny.
