Fig. 2: Preparation and characterization of HPNAs.

a Chemical structures of DTX homodimeric prodrugs. b Particle size distribution of HPNAs. Source data are provided as a Source Data file. c Morphology of HPNAs obtained by TEM. Scale bar represents 200 nm. Experiment was repeated three times independently with similar results. d Storage stability of HPNAs at 4 °C. Data are presented as mean ± SD (n = 3 independent experiments). Source data are provided as a Source Data file. e Particle size change of HPNAs after co-incubation with fetal bovine serum-containing PBS for 24 h. Data are presented as mean ± SD (n = 3 independent experiments). Source data are provided as a Source Data file.