Fig. 4: HTLV-1 specific Tax protein detected on the aGVHD skin tissues by IMC. | Nature Communications

Fig. 4: HTLV-1 specific Tax protein detected on the aGVHD skin tissues by IMC.

From: HTLV-1 infection of donor-derived T cells might promote acute graft-versus-host disease following liver transplantation

Fig. 4: HTLV-1 specific Tax protein detected on the aGVHD skin tissues by IMC.The alternative text for this image may have been generated using AI.

Representative IMC images of two independently stained skin tissues from 7 aGVHD patients show the overlap of Tax (red), DNA (blue) and different immune response markers. Displayed channels for each column were: A Tax (red)/DNA (blue); B CD4 (green)/Tax (red)/EIF1AY (white)/DNA (blue); C C4d (green)/Tax (red)/EIF1AY (white)/DNA (blue); D CD68 (green)/Tax (red)/EIF1AY (white)/DNA (blue). E Tax (red)/DNA (blue); F CD4 (green)/Tax (red)/DNA (blue); G C4d (green)/Tax (red)/DNA (blue); H CD68 (green)/Tax (red)/DNA (blue). Red arrows pinpoint the multi-signals overlap position and red boxes show the magnified view of CD4+T cells with Tax signal. Scale bar = 100 μm for landscape view and scale bar = 20 μm for magnified view.

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