Fig. 2: Safety and biocompatibility of ophthalmic SSOE.
From: Perfluorodecalin-based oxygenated emulsion as a topical treatment for chemical burn to the eye
a Representative images of live/dead assay of human corneal epithelial cells (hCECs), human corneal fibroblast cells (hCFCs), and human corneal endothelial cells (hCEnCs) after 1 h exposure to culture media, PBS, unoxygenated vehicle control, or SSOE (scale bar represents 100 μm). Percentages of dead cells in hCECs (b), hCFCs (c), and hCEnCs (d) in SSOE group were comparable or lower than those in culture media and controls. Data are presented as mean ± SEM. hCECs: n = 5, 5, 3, 5 individual samples in media, PBS, vehicle and SSOE-treated groups, respectively; hCFCs and hCEnCs: n = 5 individual samples in each group. e Slit lamp photography showing no signs of ocular redness, irritation, or inflammation 4 h after topical application of SSOE or vehicle controls. (i) Broad beam lighting, (ii) slit beam lighting, (iii) fluorescein staining, and (iv) anterior segment-OCT. Data are representative of three independent experiments. Source data are provided as a Source Data file.
