Table 1 Nucleases and base editor amino acid length vs. reference SpCas9

From: Compact Cas9d and HEARO enzymes for genome editing discovered from uncultivated microbes

Enzyme

Length (aa)

ABE length (aa)

CBE length (aa)

MG34-1

748

969

1104

MG35-1

429

623

–

SpCas9

1376

1588

1723

CasMINI (type V)

529

–

–

  1. Base editor (ABE or CBE) size for constructs tested here comprise the effector, linkers, NLS, and one deaminase monomer.
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