Table 1 Characteristics of HF patients and non-HF controls in the MVP participants of European Ancestry
From: Genetic architecture of heart failure with preserved versus reduced ejection fraction
Group | Control (N = 258,943) | HFpEF (N = 19,589) | HFrEF (N = 19,495) | Unclassified HF (N = 43,344) |
|---|---|---|---|---|
Age (years), mean±SD | 62.74 ± 13.76 | 69.88 ± 9.77 | 69.29 ± 9.74 | 69.61 ± 9.74 |
Male (%) | 92.14 | 95.74 | 97.85 | 96.92 |
Body mass index (kg/m2), mean ± | 29.20 ± 5.53 | 31.95 ± 6.98 | 30.20 ± 6.38 | 31.08 ± 6.73 |
Underweight (<18.5) % | 0.56 | 0.47 | 0.59 | 0.52 |
Normal (18.5–24.9) % | 20.25 | 13.43 | 18.79 | 16.05 |
Overweight (25.0–29.9) % | 40.66 | 29.71 | 35.09 | 32.44 |
Obese (30.0–34.9) % | 24.70 | 27.08 | 25.62 | 26.37 |
Morbidly obese (≥35.0) % | 13.84 | 29.31 | 19.91 | 24.62 |
LVEF, mean ± SD | NA | 56.97 ± 5.65 | 29.33 ± 9.36 | 43.36 ± 15.05 |
Atrial fibrillation (%) | 6.33 | 30.80 | 37.83 | 34.44 |
Coronary artery disease (%) | 22.47 | 63.87 | 74.63 | 69.72 |
Chronic kidney disease (%) | 9.54 | 37.21 | 35.75 | 36.43 |
Diabetes (%) | 20.61 | 48.54 | 45.06 | 46.76 |
Hyperlipidemia (%) | 66.9 | 87.75 | 88.20 | 88.04 |
Hypertension (%) | 62.97 | 93.22 | 91.69 | 92.51 |
Peripheral vascular disease (%) | 15.18 | 42.47 | 42.27 | 42.47 |
Stroke/TIA (%) | 8.26 | 25.29 | 24.33 | 24.93 |
