Fig. 2: Manhattan plot for basal cell carcinoma susceptibility.
The Manhattan plot shows the association between SNPs and basal cell carcinoma susceptibility based on the MTAG approach. The Y-axis represents the level of significance recorded in negative log 10 (P value) (two-tailed test), whilst the X-axis represents the chromosome 1–22, alternated with light blue and light pink colours. The horizontal blue line represents a suggestive level of significance at P value = 10−6, while the red one represents the genome-wide level of significance; P = 5 × 10−8. The green dots represent the 78 genome-wide significant independent loci for basal cell carcinoma susceptibility (after multiple correction for a million tests; 0.05/1,000,000). Only SNPs with a P value <0.01 were included. The source data file is provided as the BCC summary statistics in the GWAS Catalogue under accession code GCST90137411.
