Fig. 1: CYFIP regulates the amount and quality of night-time sleep.
From: SREBP modulates the NADP+/NADPH cycle to control night sleep in Drosophila
a Representative sleep profile of control (black, n = 38) and Cyfip85.1/+ (gray, n = 39) flies. Mean ± S.E.M. b, c Quantification of night sleep amount (b) and Consolidation Index (CI) at night (c) in control (n = 75) and Cyfip85.1/+ (n = 75) flies. Two-tailed unpaired Student’s t test, ****p < 0.0001. Mean ± S.E.M. d Waking response after sleep perturbation at ZT16, ZT18 and ZT20 (marked by “*”) in control (n = 24) and Cyfip85.1/+ (n = 29) flies. Sleep loss is measured as the ratio between sleep after stimuli and the baseline sleep. Two-tailed unpaired Student’s t test, *p = 0.015. Mean ± S.E.M. e Sleep deprivation (12 h) and sleep profile of control (n = 42) and Cyfip85.1/+ (n = 40) flies. Two-tailed unpaired Student’s t test, ****p < 0.0001. Mean ± S.E.M. Source data are provided as a Source Data file.
