Fig. 5: Illustration of using APRI to classify patients in asymptomatic screening and suspected liver disease populations. | Nature Communications

Fig. 5: Illustration of using APRI to classify patients in asymptomatic screening and suspected liver disease populations.

From: Systematic review and individual-patient-data meta-analysis of non-invasive fibrosis markers for chronic hepatitis B in Africa

Fig. 5

Using A rule-in and rule-out thresholds, B the WHO recommended threshold and C Youden J derived thresholda. aA single grey dot represents one person with liver stiffness measurement (LSM) < 7.9 kPa, one orange dot represents a person with LSM > 7.9 kPa associated with significant fibrosis, and one red dot represents a person with LSM > 12.2 kPa associated with cirrhosis (F4). Individual proportions rounded to nearest whole individual and represent the effect of applying APRI thresholds to the average populations included in the cohorts, stratified by reason for hepatitis B testing. Source data are provided as a Source Data file.

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