Fig. 9: EXO1 deficiency leads to 53BP1 bodies accumulation.
From: A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene
Quantification of immunofluorescence analysis against 53BP1 nuclear bodies in G1 (cyclin A negative cells) in RPE-1 WT, EXO1 KO7, or EXO1 KO11 cells, untreated or treated 100 µM formaldehyde for 18 h. The histogram presents the percentage of G1 cells corresponding to different number of 53BP1 bodies. Data are shown with mean ± SEM from three independent experiments.
