Fig. 6: Volume CLEM and segmented models of the separation of the protein corona and PS NPs.
From: Endosomal sorting results in a selective separation of the protein corona from nanoparticles
PS NPs with Cy5-labeled protein corona were incubated with RAW264.7 cells and imaged in CLEM after 2 h + 24 h. a Volume CLEM of the separation of protein corona and PS NPs in endosomes. a′ Front view of the segmented model in a. a″. Side view of the segmented model in a. a‴. Top view of the segmented model in a. b. Volume CLEM of an MVB with separated protein corona and PS NPs. b′. Front view of segmented model in b. b″. Side view of segmented model in b. b‴. Top view of segmented model in b. Red represents the Cy5-labeled protein corona, green represents BODIPY-labeled PS NPs, yellow represents the overlay of the protein corona and PS NPs. Scale bars: 500 nm.
