Table 2 SV discovery accuracy on HG002

From: Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak

 

DeBreak

Sniffles

pbsv

cuteSV

PAV

 

Rec

Pre

F1

Rec

Pre

F1

Rec

Pre

F1

Rec

Pre

F1

Rec

Pre

F1

Deletion

CLR

97.73

96.48

97.10

95.14

96.69

95.91

95.28

96.21

95.74

97.31

94.18

95.72

–

–

–

HiFi

98.16

95.11

96.61

97.45

91.67

94.47

96.74

94.88

95.80

97.71

93.33

95.47

96.60

96.40

96.50

Nano

98.40

95.07

96.71

96.29

94.62

95.45

97.40

81.08

88.50

98.18

89.27

93.51

–

–

–

Insertion

CLR

97.15

93.36

95.22

88.38

89.58

88.98

93.22

83.43

88.05

95.40

81.67

88.00

–

–

–

HiFi

97.26

92.84

95.00

90.90

87.79

89.32

97.41

80.42

88.10

96.64

89.88

93.14

96.18

91.32

93.69

Nano

97.46

93.91

95.65

90.57

90.01

90.29

95.07

85.60

90.09

96.99

89.27

92.97

–

–

–

  1. The unit for recall, precision, and F1 score is %. The highest recall, precision, and F1 score among four tested SV callers are marked in bold.
  2. Rec Recall, Pre Precision, F1 F1 score, Nano Nanopore, – not applicable.