Fig. 1: Designer minimalistic peptide droplets.
From: Biomolecular condensates formed by designer minimalistic peptides
a Chemical structure of WGR-1. Aromatic amino acid side chains (Trp and Tyr) are colored in blue, Arg side chain is colored in turquoise, and non-polar amino acid side chains that are part of the ELP domain (Pro-Gly-Val-Gly) are colored in orange. b Suggested mechanism of the peptide liquid droplet formation and subsequent partitioning of fluorescent payloads. c Expected intermolecular interactions underlying LLPS of WGR-1 into liquid droplets, including (from left to right) Trp-Trp, Trp-Tyr, Arg-Trp, and Arg-Tyr π-π stacking. Chemical structures of side chains are presented, color coded as described in (a).
