Fig. 5: Efferocytosis and DC-10 in Study 2. | Nature Communications

Fig. 5: Efferocytosis and DC-10 in Study 2.

From: HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC

Fig. 5: Efferocytosis and DC-10 in Study 2.The alternative text for this image may have been generated using AI.

a Correlation between the frequency of CD14+ efferocytes cocultured for 24 h and Time of Acquisition (TOA) in n = 9 vaccinated animals (week 13). b, c Correlation between the change from baseline to week 14 in the frequency of DC-10 cells and the frequency of CD14+ efferocytes cocultured for (b) 24 h in n = 9 vaccinated animals (week 13) or (c) the TOA in n = 11 vaccinated animals. Gating strategy: high SSC/single cells/Live/CD45+/Lin−(CD3−CD20−)/HLA-DR+/ CD1c−/CD11b+/CD11c+/CD14+CD16+/CD163+/CD141+/CD1a−. The frequency of DC-10 cells was identified as the frequency of CD1a− cells in CD11b+ cells. Correlation analyses: a–c Two-tailed Spearman correlation test and simple linear regression. Displayed p values are unadjusted. Source data are provided in the Source Data file.

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