Fig. 6: Model structures of PaKEOPS complexes.
From: A paralog of Pcc1 is the fifth core subunit of the KEOPS tRNA-modifying complex in Archaea
The structures of the three complexes modelled against the scattering data are shown. Calculated molecular mass from sequence and from scattering data and the deduced stoichiometry are indicated at the bottom. The subunits are colored as follows: Cgi121 (tan), Bud32 (violet), Kae1 (red), Pcc1 (blue), and Pcc2 (orange) CBKP1 and CBKP2 are dimers of two heterotetramers whereby Pcc1 and Pcc2 serve as dimerization platform, respectively. CBKP2 superdimer adopts much more open conformation with the two heterotetramers pointing into opposite directions. CBKP1P2 is a heteropentamer with Pcc2 protein engaging the Pcc1 via its dimerization interface.
