Fig. 6: Phase space structure of the 2-Mbp Chr21 organization.

t-SNE projections are calculated from the conformations and the agglomerative clustering results. Individual conformation is projected onto a two-dimensional manifold using t-SNE. Contour lines of the density of t-SNE projections are shown to reflect the underlying clusters of the conformations. The conformations naturally partition into two clusters (cluster #1 and cluster # 2 marked by blue and orange, respectively). A representative conformation from each cluster and the mean distance map computed from the conformations belonging to each cluster are also displayed.