Fig. 4: Manhattan plot of TWAS results by OTTERS.
From: OTTERS: a powerful TWAS framework leveraging summary-level reference data
Manhattan plot of TWAS results by OTTERS using GWAS summary-level statistics of cardiovascular disease and imputation models fitted based on eQTLGen summary statistics. The x-axis represented the genomic position, and the y-axis represented –log10(p values). p values were the genomic-control corrected p values from the Z-score test from TWAS (two-sided). Independently significant TWAS risk genes were labeled.
