Fig. 9: Overexpression of SERPINA3 in human macrophages rescues overwhelming cytokines in response to LPS.

a, b Real-time PCR analyses demonstrating cytokine transcripts in PBS- or LPS-treated monocyte-derived macrophages (a) or THP-1 cells (b) with or without SERPINA3- or SOCS1-lentivirus infection as indicated. Ctrl, Control. Data are shown as mean ± SD. Two-way two-sided ANOVA was performed for statistical analyses.