Fig. 5: Neutralizing antibodies avoid glycan straps to recognize conserved epitopes on prefusion NiV F.
From: Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein
Surface representation of prefusion NiV F. Individual NiV F protomers are colored in shades of pale yellow and glycans are colored in gold. Neutralizing antibody epitopes reported in this paper are painted according to the colors in Figs. 3–4. A Top and side views. B–D Zoomed views of the apical (B), lateral (C) and basal (D) surfaces of NiV F. Surface residues on the F protein are colored by sequence conservation (red is least conserved; blue is most conserved). Sequence conservation is based on the alignment shown in Supplementary Figure 11. Solid lines denote the borders of antibody epitopes.
