Fig. 5: Details of the molecular interactions between NDV L and P proteins.

a A cartoon representation of NDV L-P complex structure. The black boxes indicate the magnified view of the interactions between L and P. b–d Magnified views of interaction interfaces between L and P proteins. The representative residues involved in interaction are shown, main chain or side chains involved in hydrogen bonds or hydrophobic interactions are shown as sticks, with oxygen and nitrogen atoms shown in red and blue, respectively. Electrostatic interactions are depicted as dashed lines. e L and P proteins are shown as molecular surfaces colored by electrostatic potential from red to blue, negative to positive, respectively. The surface of each protein is shown in an open-book representation. The approximate binding interface is outlined in yellow. A region of electrostatic complementarity is highlighted with a dashed oval.