Fig. 2: Extracellular interfaces of MmSVCT1.
From: Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter
a One subunit of MmSVCT1 viewed from the gate domain with a zoomed-in view of interface I. The TM13 helix was removed for clarity. The central pore calculated by the program Hole is shown as a dotted mesh. b Magnified view of interface II. c Transport activity of MmSVCT1 variants with point mutations at the extracellular interface. Data points are the mean ± SEM (n = 5 independent experiments). P values from the two-tailed t-test are indicated on the bar chart. Source data are provided as a Source Data file.
