Fig. 3: Vitamin C and sodium ion binding in MmSVCT1.
From: Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter
a Residues in the proximity of the vitamin C molecule. Sodium ions are shown as blue spheres, and a potential water molecule (Wat) is shown as a red sphere. Interactions are indicated by dashed lines. b Coordinating residues of Na1. c Uptake activity of MmSVCT1 variants with point mutations at vitamin C and sodium ion binding sites. Data points are the mean ± SEM (n = 5 independent experiments). P values from the two-tailed t-test are indicated on the bar chart. Source data are provided as a Source Data file.
