Fig. 4: T cell receptor excisions circle (TREC) and single cell RNA-seq analysis confirms peripheral expansion of intestinal T cells. | Nature Communications

Fig. 4: T cell receptor excisions circle (TREC) and single cell RNA-seq analysis confirms peripheral expansion of intestinal T cells.

From: Immune subset-committed proliferating cells populate the human foetal intestine throughout the second trimester of gestation

Fig. 4

a Proliferative history in human fetal intestinal samples (n = 3). Error bars indicate mean ± SD. b–d t-SNE embedding showing 1804 CD4+ T cells from a human fetal intestine analyzed by single-cell RNA-sequencing. The log-transformed expression levels of indicated immune markers (b), the phase of the cell-division cycle (c) and genes involved in TCR rearrangement (d) are shown. Each dot represents a single cell. The proliferative CD4+ T cells are encircled (b).

Back to article page