Fig. 5: Sex-specific changes in microbiota-associated metabolism. | Nature Communications

Fig. 5: Sex-specific changes in microbiota-associated metabolism.

From: Microbiota alters the metabolome in an age- and sex- dependent manner in mice

Fig. 5: Sex-specific changes in microbiota-associated metabolism.The alternative text for this image may have been generated using AI.

A Biplot showing the Log2FC in metabolites that were significantly different (PAdj <0.05) in male vs. female SPF mice or male vs. female GF mice. Metabolites were significantly different based on age in either GF (red) or SPF (green) or in both GF and SPF (blue). B Violin plots of highlighted metabolites from A that are differentially affected by colonization in male and female mice. Data shown for GF, OMM12 and SPF colonized male and female mice. Data represented 8 mice/group. GF germ-free, OMM12 Oligo-MM12, SPF specific pathogen free, F female, M male. Source data are provided as a Source Data file.

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